This edition of the Research Video Series features the HD Buzz article, Two Birds One Stone. In a surprising twist, oral HTT-lowering drugs also slow somatic expansion in the HTT gene. A new study that used cells in a dish for this fortuitous discovery identified the gene PMS1 as a key player in the slowing of CAG expansions.

Read the entire HD Buzz article, https://en.hdbuzz.net/367

The Research Video Series is sponsored by Roche, Sage Therapeutics, Teva Pharmaceutical, uniQure, Wave Life Sciences, Griffin Foundation and Neurocrine Biosciences.